Greedy clustering of count data through a mixture of multinomial PCA

Abstract

Count data is becoming more and more ubiquitous in a wide range of applications, with datasets growing both in size and in dimension. In this context, an increasing amount of work is dedicated to the construction of statistical models directly accounting for the discrete nature of the data. Moreover, it has been shown that integrating dimension reduction to clustering can drastically improve performance and stability. In this paper, we introduce the mixture of multinomial PCA, a new mixture model for the clustering of count data. Related to the latent Dirichlet allocation model, it offers the flexibility of topic modeling while being able to assign each observation to a unique cluster. We propose an inference procedure, where inference and clustering are jointly done by mixing a classification variational expectation maximization algorithm, with a branch & bound like strategy on a variational lower bound. An integrated classification likelihood criterion is derived for model selection, and a thorough study with numerical experiments is proposed to assess both the performance and robustness of the method. Finally, we illustrate the qualitative interest of the latter in a real-world application, for the clustering of anatomopathological medical reports, in partnership with expert practitioners from the Institut Curie hospital.

The R package is currently under devellopment and only available at my GitHub page, but it should appear on CRAN soon.

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Nicolas Jouvin
INRAE researcher in Applied Mathematics